HORDB

ID: hor002637
Uniprot ID: G5EGN6
Protein name: NLP-15
Gene name: nlp-15
Organism: Caenorhabditis elegans
Family: NA
Source: animal
Expression: NA
Disease: NA
Comments: NA
Taxonomy: Caenorhabditis (genus), Peloderinae (subfamily), Rhabditidae (family), Rhabditoidea (superfamily), Rhabditomorpha (infraorder), Rhabditina (suborder), Rhabditida (order), Chromadorea (class), Nematoda (phylum), Ecdysozoa, Protostomia, Bilateria, Eumetazoa, Metazoa (kingdom), Opisthokonta, Eukaryota (superkingdom), cellular organisms
GO MF: GO:0005184 neuropeptide hormone activity
GO BP: GO:0007218 neuropeptide signaling pathway
GO CC: NA

Sequence: AFDSLAGQGFTGFE
Length: 14(113-126)
Propeptide: MPSSSSSSSFFAAVLLVIVMMSTVESAAVRLRPVGSLFFLNRPHEKRAFDSLAGSGFDNGFNKRAFDSLAGSGFGAFNKRAFDSLAGSGFGAFNKRAFDSLAGSGFSGFDKRAFDSLAGQGFTGFEKRAFDTVSTSGFDDFKL
Signal peptide: MPSSSSSSSFFAAVLLVIVMMSTVES
Modification: NA
Glycosylation: NA
Mutagenesis: NA

Structure: (PDB_ID-from https://www.rcsb.org/; AlphaFold_DB_ID-from https://alphafold.ebi.ac.uk/; hordbxxxxxx_AF2.pdb was predicted structure by AlphaFold2; hordbxxxxxx_ESM.pdb was predicted structure by ESMFold)

hor002637_AF2.pdb

hor002637_ESM.pdb

Mass:	167860	Formula:	C66H91N15O22
Absent amino acids:	CHIKMNPRVWY	Common amino acids:	FG
pI:	3.55	Basic residues:	0
Polar residues:	5	Hydrophobic residues:	6
Hydrophobicity:	18.57	Boman Index:	-674
Half-Life:	4.4 hour	Half-Life Yeast:	>20 hour
Half-Life E.Coli:	>10 hour	Aliphatic Index	42.14
Instability Index:	2579.29	Extinction Coefficient cystines:	0
Absorbance 280nm:	0

PubMed ID: 20013198
Title: Approaches to Identify Endogenous Peptides in the Soil Nematode Caenorhabditis elegans